Thursday, April 21, 2022

2022-04-21 / 10:00 ~ 12:30

학과 세미나/콜로퀴엄 - 기타:

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2022-04-21 / 16:00 ~ 17:00

IBS-KAIST 세미나 - 수리생물학:

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Metastasis and therapy resistance cause over 90% of cancer-related deaths. Despite extensive ongoing efforts, no unique genetic or mutational signature has emerged for metastasis. Instead, the ability of genetically identical cells to adapt reversibly by exhibiting multiple phenotypes (phenotypic/non-genetic heterogeneity) and switch among them (phenotypic plasticity) is proposed as a hallmark of metastasis. Also, drug resistance can emerge from such non-genetic adaptive cellular changes. However, the origins of such non-genetic heterogeneity in most cancers are poorly understood. I will present our findings on a) how non-genetic heterogeneity emerges in a population of cancer, and b) what design principles underlie regulatory networks enabling non-genetic heterogeneity across multiple cancers. Our results unravel how systems-levels approaches integrating mechanistic mathematical modeling with in vitro and in vivo data can identify causes and consequences of such non-genetic heterogeneity.

2022-04-27 / 16:00 ~ 17:00

IBS-KAIST 세미나 - IBS-KAIST 세미나:

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In this talk, we will discuss a complete classification of proper holomorphic maps from the unit ball in complex two dimensional space into the Cartan’s classical domain of type IV in complex three dimensional space that extend smoothly to some boundary point. This classification (which is a consequence of a classification of CR maps from the 3-sphere into the tube over the future light cone) consists of 4 algebraic maps. Among them, two previously known maps are isometric with respect to the canonical Bergman metrics and two other maps give counterexamples to a recent conjecture of Xiao-Yuan for the case of maps from the complex 2-ball. This is a joint work with Michael Reiter.

2022-04-26 / 12:00 ~ 12:50

대학원생 세미나 - 대학원생 세미나: 해외 수학과 포닥 지원은 어떻게 하는가

by 최두성(KAIST)

I will present how to apply for the abroad postdoc position. Basically, I will explain how to prepare the CV, recommendation letters, research statement, teaching statement, diversity statement, etc., which are necessary documents to apply postdoc. The timelines for the postdoc application of the universities in the U.S. and Europe are very different from Korean universities. I will share a variety of information about when, where, and who you can apply for the postdoc position.

2022-04-25 / 16:30 ~ 17:30

IBS-KAIST 세미나 - 이산수학: Odd coloring of sparse graphs

by 박보람(아주대)

We introduce an odd coloring of a graph, which was introduced very recently, motivated by parity type colorings of graphs. A proper vertex coloring of graph $G$ is said to be odd if for each non-isolated vertex $x \in V (G)$ there exists a color $c$ such that $c$ is used an odd number of times in the neighborhood of $x$. The recent work on this topic will be presented, and the work is based on Eun-Kyung Cho, Ilkyoo Choi, and Hyemin Kown.

2022-04-28 / 16:15 ~ 17:15

학과 세미나/콜로퀴엄 - 콜로퀴엄:

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We study stability of a spherical vortex introduced by M. Hill in 1894, which is an explicit solution of the three-dimensional incompressible Euler equations. The flow is axi-symmetric with no swirl, the vortex core is simply a ball sliding on the axis of symmetry with a constant speed, and the vorticity in the core is proportional to the distance from the symmetry axis. We use the variational setting introduced by A. Friedman and B. Turkington (Trans. Amer. Math. Soc., 1981). As a consequence, the stability up to a translation is obtained by using a concentrated compactness method. As an application, we prove linear in time filamentation near Hill’s vortex: there exists an arbitrary small outward perturbation growing linearly for all times. These results rigorously confirm numerical simulations by Pozrikidis in 1986. The second part is joint work with In-Jee Jeong(SNU).

2022-04-28 / 11:00 ~ 12:00

IBS-KAIST 세미나 - 수리생물학:

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Outputs from health biological systems display complex fluctuations that are not random but display robust and often self-similar (fractal) temporal correlations at different time scales— scaling behaviors. The scaling behaviors in the fluctuations of biological outputs such as neural activities, cardiac dynamics, motor activity are believed to be originated from feedbacks within the complex biological networks, reflecting the system adaptability to internal and external inputs. Supporting this concept, our studies have demonstrated a mechanistic link between the scaling regulation of physiological fluctuations and the circadian control system— a result of evolutionary adaptation to daily environmental light-dark cycles on the earth. In this talk, I will discuss certain evidence for this ‘scaling-circadian’ link and its related implications. Moreover, I will review some recent studies, in which we examined how the scaling patterns of human motor activity fluctuations change with aging and in Alzheimer’s disease. Our results showed that (1) alterations in scaling activity patterns occur before the clinical manifestation of Alzheimer’s disease (i.e., cognitive impairment) and predict cognitive decline and the risk for Alzheimer’s dementia; and (2) the progression of Alzheimer’s disease accelerates the aging effect on the scaling activity patterns. Our work provides strong evidence that altered scaling activity patterns may also be a risk factor for neurodegeneration, playing a role in the development and progression of Alzheimer’s disease.

Events for the 취소된 행사 포함